Cycloartane Glycosides from Sutherlandia frutescens
نویسندگان
چکیده
منابع مشابه
Flavonol glycosides from the south African medicinal plant Sutherlandia frutescens.
Phytochemical investigation of the leaves of Sutherlandia frutescens led to the isolation of four new 3-hydroxy-3-methylglutaroyl-containing flavonol glycosides, sutherlandins A-D ( 1- 4). Their structures were elucidated by chemical and spectroscopic methods as quercetin 3- O- beta- D-xylopyranosyl(1 --> 2)-[6- O-(3-hydroxy-3-methylglutaroyl)]- beta- D-glucopyranoside ( 1), quercetin 3- O- bet...
متن کاملShort communication. Challenges relating to comparison of flavonoid glycosides dissolution profiles from Sutherlandia frutescens products.
Unlike the case of conventional drug formulations, dissolution tests have hitherto not been required for herbal medicinal products commercially available in South Africa. This study investigated dissolution of the South African Sutherlandia frutescens using selected flavonoid glycosides as marker compounds. Dissolution of markers was assessed in three dissolution media at pH 1.2, 4.5 and 6.8, a...
متن کاملCycloartane glycosides from Cimicifuga dahurica.
A new cycloartane bisdesmoside and two new trinorcycloartane glycosides, along with four known cycloartane compounds, were isolated from the rhizomes of Cimicifuga dahurica (Ranunculaceae). The structures of the new compounds were elucidated as 3-O-alpha-L-arabinopyranosyl cimigenol 15-O-beta-D-glucopyranoside, 24-hydroxy-12beta-acetoxy-25,26,27-trinorcycloartan-16,23-dione 3beta-O-alpha-L-arab...
متن کاملCycloartane Glycosides from Astragalus erinaceus
One new cycloartane-type saponin, 3-O-[β-D-xylopyranosyl-(1→2)-β-D-xylopyranosyl]-6-O-β-Dglucuronopyranosyl-3β,6α,16β,24(S),25-pentahydroxyxyxloartane (1) was isolated from the MeOH extract of whole plant parts of Astragalus erinaceus along with 5 known saponins (2-6), cyclodissectoside, cycloastragenol, 6-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane, oleifolioside B and 3,6d...
متن کاملThree new 15,16-seco-cycloartane glycosides from Cimicifuga Rhizome.
Three new 15,16-seco-cycloartane glycosides, which were constructed by a C-C bond cleavage in the D ring, have been isolated from Cimicifuga Rhizome for the first time. Their structures were determined by the use of 2D NMR techniques and chemical evidence.
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ژورنال
عنوان ژورنال: Journal of Natural Products
سال: 2008
ISSN: 0163-3864,1520-6025
DOI: 10.1021/np800328r